Rejuran
Rejuran is an injectable polynucleotide (PN) treatment: purified DNA fragments derived from salmon, delivered into the skin in a grid of small, shallow injections. It is made by a Korean manufacturer, has been on Seoul dermatology menus since the mid-2010s, and on the local menu it is a maintenance item, sold as sessions and short courses, not as an event.
The product is a polynucleotide gel, DNA fragments purified from salmon, injected intradermally across the treated area. A session is a grid of many small injections rather than a few deep ones. It is a distinct category from botulinum toxin (which acts on muscle) and from filler (which adds volume); on a Korean menu the three are separate columns, not substitutes.
Locals reach for Rejuran when the complaint is the skin itself (texture, thinness, the tired look) rather than a line or a hollow. The recurring search "what Koreans get instead of filler" mostly resolves to this distinction: it is not that locals found a secret substitute for filler, it is that they are often buying for skin quality, where filler was never the tool.
On the calendar it behaves like maintenance: a short course spaced weeks apart, then single sessions on a cycle the doctor sets. See what a local maintenance calendar looks like.
The local menu lists Rejuran per session, with course pricing below it. Visitor quotes often bury it inside a multi-treatment package where the line item disappears, which makes comparison impossible by design. We book at the clinic's local list price; our fee is a separate line on the quote. Structure, not amounts: prices belong to clinics and differ between them. The mechanism is on the local price.
Cosmetic and short. The injection grid is visible as small raised points that settle over the first days, and clinics commonly ask you to hold makeup off the treated area briefly. If your trip is tight this is scheduling information, not a disqualifier. It just belongs early in the itinerary. Your clinic's aftercare instructions are the binding version.
This page describes what a treatment is and how locals buy it. It is not medical advice, it promises no outcome, and it names no clinic. Whether any treatment suits you is a question for a doctor who has seen your skin. Last checked: 30 July 2026.